Antitussive Drugs

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*Codeine*

#Formulations : Tablet , Linctus

#Brand_Names : Codine

#Pharmacological_Action : It directly acts on the CNS to raise the cough centre or act peripherally in the respiratory tract to reduce tussal impulse.

#Side_Effects : Insomnia, Respiratory Depression.


#Therapeutic_Uses : used as antitussive Drugs.

*Ethylmorphine*

#Formulations : Tablet

#Brand_Names : Dionindon

#Pharmacological_Action : It is closely related to codeine which is methylmorphine and has antitussive respiratory depression properties like it, but is believed to be less constipating.


#Dose: 10-30 mg TDS.

#Therapeutic_Uses : used as antitussive Drugs.

*Pholcodine*

#Formulations : NA

#Brand_Names : NA

#Pharmacological_Action : It has practically no analgesic or addicting property.

#Dose : 10-15 mg

#Therapeutic_Uses : used as antitussive Drugs.

*Noscapine*

#Formulations : Tablet, Syrup

#Brand_Names : Coscopin, Coscotabs

#Pharmacological_Action : An opium alkaloid of the benzoisoquinoline series, which depresses cough but has no narcotic, analgesics or dependence inducing properties.


#Dose : 15-30 mg


#Therapeutic_uses : used as antitussive Drugs.

*Dextromethorphan*

#Formulations : NA

#Brand_Names : NA

#Pharmacological_Action : A synthetic central NMDA receptor antagonist; the d-isomer has antitussive action while l-isomer is analgesic. It does not supress mucociliary function.

#Side_Effects : Dizziness, Nausea, Drowsiness

#Dose : 10- 20 mg

#Therapeutic_Uses : used as antitussive Drugs.

*Prenoxdiazine*

#Formulations : Tablet

#Brand_Names : Prenoxid

#Pharmacological_Action : It desensitizes the pulmonary stretch receptors.


#Dose : 100- 200 mg


#Therapeutic_Uses : used as antitussive Drugs.